Chemical Acute Exposure Guideline Levels (AEGLs)

The Environmental Protection Agency has listed a group of chemicals to prevent acute exposure to in the future environment. This list includes very toxic chemicals to humans, animals and plants. First AEGL Chemical Priority List The First AEGL Chemical Priority List appeared in the May 21, 1997 Federal Register Page 27733-27734 and listed 85 chemicals. An additional 15 chemicals were added to this list subsequently. All 100 First AEGL Chemical Priority List chemicals were viewed as high priority for AEGL development, based on their nomination by AEGL Committee stakeholders and overlap of interest among many different organizations. CAS No. Chemical Name 56-23-5................................... Carbon tetrachloride 57-14-7................................... 1,1-Dimethyl hydrazine 60-34-4................................... Methyl hydrazine 62-53-3................................... Aniline 67-56-1................................... Methanol 67-66-3................................... Chloroform 68-12-2................................... Dimethylformamide 71-43-2................................... Benzene 74-90-8................................... Hydrogen cyanide 74-93-1................................... Methyl mercaptan 75-09-2................................... Methylene chloride 75-21-8................................... Ethylene oxide 75-44-5................................... Phosgene 75-55-8................................... Propyleneimine 75-56-9................................... Propylene oxide 75-74-1................................... Tetramethyllead 75-77-4................................... Trimethychlorosilane 75-78-5................................... Dimethyldichlorosilane 75-79-6................................... Methyltrichlorosilane 75-86-5................................... Acetone cyanohydrin 77-81-6................................... Tabun (GA) 78-82-0................................... Isobutyronitrile 78-93-3................................... Methyl ethyl ketone 79-01-6................................... Trichloroethylene 79-10-7................................... Acrylic acid 79-11-8................................... (mono-)Chloroacetic acid 79-21-0................................... Peracetic acid 79-22-1................................... Methyl chloroformate 91-08-7................................... Toluene 2,6-diisocyanate 96-64-0................................... Soman (GD) 106-89-8................................. Epichlorohydrin 107-02-8................................. Acrolein 107-11-9................................. Allyl amine 107-12-0................................. Propionitrile 107-15-3................................. Ethylenediamine 107-18-6................................. Allyl alcohol 107-30-2................................. Chloromethyl methyl ether 107-44-8................................. Sarin (GB) 108-23-6................................. Isopropyl chloroformate 108-88-3................................. Toluene 108-91-8................................. Cyclohexylamine 108-95-2................................. Phenol 109-61-5................................. Propyl chloroformate 110-00-9................................. Furan 110-89-4................................. Piperidine 123-73-9................................. Crotonaldehyde, (E) 123-91-1................................. 1,4-Dioxane 126-98-7................................. Methacrylonitrile 127-18-4................................. Tetrachloroethylene 151-56-4................................. Ethyleneimine 302-01-2................................. Hydrazine 329-99-7................................. Cyclohexylmethyl phosphono fluoridate GF 353-42-4................................. Boron triflouride compound with methyl ether (note: boron trifluoride CAS # is 7637-07-2) 505-60-2................................. Sulfur mustard 506-77-7................................. Cyanogen chloride 509-14-8................................. Tetranitromethane 540-59-0................................. 1,2-Dichloroethylene 540-73-8................................. 1,2-Dimethylhydrazine 584-84-9................................. Toluene 2,4-diisocyanate 594-42-3................................. Perchloromethylmercaptan 624-83-9................................. Methyl isocyanate 630-08-0................................. Carbon monoxide 811-97-2................................. HFC 134A (1,1,1,2-Tetrafluoroethane) 814-68-6................................. Acrylyl chloride 1330-20-7............................... Xylenes (mixed) 1717-00-6............................... HCFC 141b (1,1-Dichloro-1-fluoroethane) 4170-30-3............................... Crotonaldehyde 6423-43-4............................... Otto Fuel II 7446-09-5............................... Sulfur dioxide 7446-11-9............................... Sulfur trioxide 7647-01-0............................... Hydrogen chloride 7647-01-0............................... Hydrochloric acid 7664-39-3............................... Hydrogen fluoride 7664-41-7............................... Ammonia 7664-93-9............................... Sulfuric acid 7697-37-2............................... Nitric acid 7719-12-2............................... Phosphorus trichloride 7726-95-6............................... Bromine 7782-41-4............................... Fluorine 7782-50-5............................... Chlorine 7783-06-4............................... Hydrogen sulfide 7783-60-0............................... Sulfur tetrafluoride 7783-81-5............................... Uranium hexafluoride 7784-34-1............................... Arsenous trichloride 7784-42-1............................... Arsine 7790-91-2............................... Chlorine trifluoride 7803-51-2............................... Phosphine 8014-95-7............................... Oleum 10025-87-3.............................. Phosphorus oxychloride 10049-04-4.............................. Chlorine dioxide 10102-43-9.............................. Nitric oxide 10102-44-0.............................. Nitrogen dioxide 10294-34-5.............................. Boron trichloride 13463-39-3.............................. Nickel carbonyl 13463-40-6.............................. Iron, pentacarbonyl- 19287-45-7.............................. Diborane 25323-89-1.............................. Trichloroethane 50782-69-9.............................. VX 163702-07-6............................ Methyl nonafluorobutyl ether (HFE 7100 component) 163702-08-7............................ Methyl nonafluorobutyl ether (HFE 7100 component) Second AEGL Chemical Priority List [New Replace Term] This list of 371 priority chemicals is a composite of numerous priority lists of acutely toxic chemicals and represents the selection of chemicals for AEGL development by the NAC/AEGL during the next several years. The list has been assembled from the individual lists of chemicals nominated by NAC/AEGL member organizations for AEGL development. The priority list of chemicals, published in notice, is subject to modification as priorities of the NAC/AEGL committee or the NAC/AEGL member organizations change, it is anticipated that most of the chemicals on the priority list will remain as higher priority for AEGL development during the next several years. The NAC/AEGL intends to address at least 30 chemicals per year in the AEGL development process. There are 137 chemicals on this list of 371 priority chemicals that are considered a higher priority (indicated by an asterisk below), based on considerations of toxicity, volatility, presence on numerous organization chemical lists, and other factors. These chemicals are planned to be addressed prior to the other listed chemicals. It is believed that publication of today's list of chemicals will provide individuals and organizations with ample time to gather existing data and information and, where appropriate, to develop new data and information on the acute toxicity of the chemicals listed herein, for the consideration of the NAC/AEGL Committee. Parties possessing such data and information or those anticipating the future conduct of toxicity studies on any of these chemicals should contact the Designated Federal Officer. Second List of AEGL Priority Chemicals for Guideline Development CAS No. Chemical Name 50-00-0................................... Formaldehyde* 50-29-3................................... 4,4'-DDT 50-32-8................................... Benzo(a)pyrene* 54-11-5................................... Nicotine 56-38-2................................... Parathion* 56-55-3................................... Benzo(a)anthracene 56-72-4................................... Coumaphos 57-24-9................................... Strychnine* 57-57-8................................... Beta-Propiolactone 57-74-9................................... Chlordane* 58-89-9................................... Lindane (hexachlorocyclohexane) 60-29-7................................... Ethyl ether 60-51-5................................... Dimethoate 60-57-1................................... Dieldrin 62-38-4................................... Phenylmercuric acetate* 62-73-7................................... Dichlorvos 62-74-8................................... Sodium fluoroacetate* 62-75-9................................... Nitrosodimethylamine 64-18-6................................... Formic acid 64-19-7................................... Acetic acid 67-64-1................................... Acetone* 74-82-8................................... Methane 74-83-9................................... Methyl bromide* 74-87-3................................... Methyl chloride* 74-88-4................................... Methyl iodide 74-89-5................................... Methyl amine* 74-98-6................................... Propane* 75-00-3................................... Chloroethane 75-01-4................................... Vinyl chloride* 75-02-5................................... Vinyl fluoride 75-04-7................................... Ethyl amine* 75-05-8................................... Acetonitrile 75-07-0................................... Acetaldehyde* 75-08-1................................... Ethyl mercaptan* 75-12-7................................... Formamide 75-15-0................................... Carbon disulfide* 75-18-3................................... Dimethyl sulfide 75-25-2................................... Bromoform 75-34-3................................... 1,1-Dichloroethane 75-36-5................................... Acetyl chloride* 75-50-3................................... Trimethylamine* 75-54-7................................... Methyl dichlorosilane* 75-65-0................................... t-Butyl alcohol 75-93-4................................... Methyl sulfate 76-02-8................................... Trichloroacetyl chloride* 76-06-2................................... Chloropicrin* 76-44-8................................... Heptachlor 77-47-4................................... Hexachlorocyclopentadiene 77-78-1................................... Dimethyl sulfate* 78-00-2................................... Tetraethyl lead 78-71-7................................... Oxetane, 3,3- bis(chloromethyl)- 78-85-3................................... Methacrylaldehyde* 78-87-5................................... 1,2-Dichloropropane 78-94-4................................... Methyl vinyl ketone* 78-95-5................................... Chloroacetone (stabilized)* 78-97-7................................... Lactonitrile 79-04-9................................... Chloroacetyl chloride* 79-06-1................................... Crylamide 79-09-4................................... Propionic acid 79-14-1................................... Glycolic acid 79-19-6................................... Thiosemicarbazide 79-38-9................................... Trifluorochloroethylene 79-41-4................................... Methacrylic acid* 79-57-2................................... Terramycin* 80-15-9................................... Cumene hydroperoxide 80-56-8................................... alpha-Pinene 80-62-6................................... Methyl methacrylate* 80-63-7................................... Methyl 2-chloroacrylate 81-81-2................................... Warfarin 82-66-6................................... Diphacinone 84-66-2................................... Diethyl phthalate 84-74-2................................... di-n-Butyl phthalate 85-68-7................................... Butyl benzyl phthalate 86-50-0................................... Azinphos-methyl* 86-74-8................................... Carbazole 87-86-5................................... Pentachlorophenol 92-52-4................................... Biphenyl 94-75-7................................... 2,4-Dichlorophenyoxy acetic acid 95-48-7................................... o-Cresol 95-63-6................................... Trimethyl benzene 96-29-7................................... 2-Butanone oxime 97-02-9................................... 2,4-Dinitroaniline* 98-05-5................................... Phenyl arsonic acid 98-07-7................................... Benzyl trichloride 98-09-9................................... Benzenesulfonyl chloride 98-13-5................................... Trichlorophenyl silane 98-16-8................................... 3-(Trifluoromethyl) Aniline 98-82-8................................... Cumene 98-87-3................................... Benzal chloride 98-88-4................................... Benzoyl chloride 98-95-3................................... Nitrobenzene 100-14-1.................................. Benzene, 1-(chloromethyl)-4- nitro- 100-41-4.................................. Ethyl benzene 100-42-5.................................. Styrene* 100-44-7.................................. Benzyl chloride 100-51-6.................................. Benzyl alcohol 101-68-8.................................. 4,4-Methylenediphenyl diisocyanate* 103-71-9.................................. Phenyl isocyanate 105-60-2.................................. Caprolactam 106-44-5.................................. p-Cresol 106-50-3.................................. p-Phenylenediamine 106-88-7.................................. 1,2-Butylene oxide 106-93-4.................................. Dibromoethane* 106-96-7.................................. Propargyl bromide 106-97-8.................................. Butane* 106-99-0.................................. Butadiene* 107-05-1.................................. Allyl chloride 107-06-2.................................. 1,2-Dichloroethane 107-07-3.................................. Chloroethanol 75-05-8.................................. Acrylonitrile* 107-14-2.................................. Chloroacetonitrile* 107-16-4.................................. Formaldehyde cyanohydrin 107-19-7.................................. Propargyl alcohol 107-20-0.................................. Chloroacetaldehyde* 107-21-1.................................. Ethylene glycol 107-37-9.................................. Allyl trichlorosilane 107-72-2.................................. Amyltrichlorosilane 108-05-4.................................. *Vinyl acetate monomer 108-10-1.................................. 4-Methyl-2-pentanone 108-24-7.................................. Acetic anhydride* 108 31-6.................................. Maleic anhydride* 108-39-4.................................. m-Cresol 108-65-6.................................. Propylene glycol monomethyl ether acetate 108-67-8.................................. Mesitylene 108-90-7.................................. Chlorobenzene* 108-98-5.................................. Phenylmercaptan* 109-73-9.................................. n-Butylamine 109-77-3.................................. Malononitrile* 109-89-7.................................. Diethyl amine 109-90-0.................................. Ethyl isocyanate 109-99-9.................................. Tetrahydrofuran* 110-54-3.................................. Hexane* 110-57-6.................................. Trans-1,4-dichlorobutene 110-78-1.................................. n-Propyl isocyanate 110-82-7.................................. Cyclohexane* 110-86-1.................................. Pyridine 111-34-2.................................. Butyl vinyl ether 111-36-4.................................. n-Butyl isocyanate* 111-42-2.................................. Diethanolamine 111-44-4.................................. Dichloroethyl ether 111-48-8.................................. Thiodiglycol 111-69-3.................................. Adiponitrile 111-77-3.................................. Diethylene glycol monomethyl ether 111-88-6.................................. n-Octylmercaptan* 115-21-9.................................. Trichloroethyl silane 116-06-3.................................. Aldicarb* 116-14-3.................................. Tetrafluoroethylene 116-15-4.................................. Hexafluoropropylene 117-84-0.................................. Dioctyl phthalate 118-52-5.................................. 1,3-Dichloro-5,5- dimethylhydantoin 120-82-1.................................. 1,2,4-Trichlorobenzene 121-75-5.................................. Malathion 122-14-5.................................. Fenitrothion 123-31-9.................................. Hydroquinone 123-38-6.................................. Propionaldehyde* 123-86-4.................................. n-Butyl acetate* 124-40-3.................................. Dimethyl amine* 124-63-0.................................. Methanesulfonyl chloride 124-65-2.................................. Sodium cacodylate 129-00-0.................................. Pyrene 131-11-3.................................. Dimethyl phthalate 140-88-5.................................. Ethyl acrylate* 141-32-2.................................. Butylacrylate* 141-43-5.................................. Monoethanolamine 141-59-3.................................. t-Octyl mercaptan 141-66-2.................................. Dicrotophos 141-78-6.................................. Ethyl acetate* 143-33-9.................................. Sodium cyanide* 144-62-7.................................. Oxalic acid 149-74-6.................................. Dichloromethylphenyl silane 150-76-5.................................. p-Methoxyphenol 151-38-2.................................. Methoxyethyl mercury* 207-08-9.................................. Benzo(k)fluoranthene 218-01-9.................................. Chrysene 287-92-3.................................. Cyclopentane 297-78-9.................................. Isobenzan 298-00-0.................................. Methyl parathion* 298-02-2.................................. Phorate* 298-04-4.................................. Disulfoton* 300-62-9.................................. Amphetamine 333-41-5.................................. Diazinon 334-88-3.................................. Diazomethane* 353-50-4.................................. Carbonyl fluoride* 354-32-5.................................. Trifluoroacetyl chloride 371-62-0.................................. Ethylene fluorohydrin 382-21-8.................................. Perfluoroisobutylenene 453-18-9.................................. Methyl fluoroacetate* 460-19-5.................................. Cyanogen* 463-51-4.................................. Ketene* 463-58-1.................................. Carbonyl sulfide* 463-71-8.................................. Thiophosgene 503-38-8.................................. Diphosgene 506-68-3.................................. Cyanogen bromide* 506-78-5.................................. Cyanogen iodide 506-96-7.................................. Acetyl bromide 534-52-1.................................. 4,6-Dinitro-o-cresol 538-07-8.................................. Bis(2-chloroethyl)ethylamine 541-25-3.................................. Lewisite 541-41-3.................................. Ethyl chloroformate* 542-88-1.................................. bis-Chloromethyl ether* 543-27-1.................................. i-Butyl chloroformate 555-77-1.................................. Tris(2-chloroethyl)amine (N- Mustard) 556-61-6.................................. Methyl isothiocyanate 556-64-9.................................. Methyl thiocyanate* 563-12-2.................................. Ethion 578-94-9.................................. Adamsite 592-34-7.................................. n-Butyl chloroformate 593-53-3.................................. Methyl fluoride 593-89-5.................................. Methyl dichloroarsine 598-14-1.................................. Ethyl dichloroarsine 598-31-2.................................. Bromoacetone 622-44-6.................................. Phenyl carbylamine chloride 624-92-0.................................. Dimethyl disulfide* 625-55-8.................................. Isopropyl formate 627-44-1.................................. Diethyl mercury 640-19-7.................................. Fluoroacetamide 646-06-0.................................. Diulane 674-82-8.................................. Diketene* 675-14-9.................................. Cyanuric fluoride 676-83-5.................................. Methyl phosphonous dichloride 676-97-1.................................. Methyl phosphonic dichloride 681-84-5.................................. Tetamethoxysilane 684-16-2.................................. Hexafluoroacetone* 696-28-6.................................. Phenyl dichloroarsine 732-11-6.................................. Phosmet 757-58-4.................................. Hexaethyl tetraphosphate 813-78-5.................................. Dimethyl phosphate 919-86-8.................................. Demeton S-methyl 920-46-7.................................. Methacryloyl chloride 944-22-9.................................. Fonofos* 950-37-8.................................. Methidathion* 993-00-0.................................. Methyl chlorosilane* 993-13-5.................................. Methylphosphonic acid 993-43-1.................................. Ethylphosphonodithioicdichlo ride 999-81-5.................................. Clormequat chloride 1024-57-3................................. Heptachlor epoxide 1120-71-4................................. 1,3-Propane sultone 1303-28-2................................. Arsenic pentoxide 1306-02-1................................. Lewisite oxide 1314-84-7................................. Zinc phosphide 1319-77-3................................. Cresol* 1327-53-3................................. Arsenic trioxide* 1336-36-3................................. Polychlorinated biphenyl 1341-24-8................................. Chloroacetophenone* 1341-49-7................................. Ammonium bifluoride 1397-94-0................................. Antimycin A 1498-40-4................................. Ethylphosphonous dichloride 1498-51-7................................. Ethylphosphorodichloridate 1558-25-4................................. Chloromethyl (trichloro) silane 1563-66-2................................. Carbofuran* 1582-09-8................................. Trifluralin 1609-86-5................................. t-Butyl isocyanate 1634-04-4................................. Methyl t-butyl ether* 1675-54-3................................. Bisphenol A diglycidyl ether 1737-93-5................................. 3,5-Dichloro-2,4,5- trifluoropyridine 1746-01-6................................. 2,3,7,8-Tetrachlorodibenzo-p- dioxin* 1832-54-8................................. Isopropyl methyl phosphonic acid 1873-29-6................................. Isobutyl isocyanate 1910-42-5................................. Paraquat dichloride* 2032-65-7................................. Methiocarb 2231-57-4................................. Thiocarbazide 2487-90-3................................. Trimethoxysilane 2524-03-0................................. Dimethyl phosphorochloridothioate 2696-92-6................................. Nitrosyl chloride* 2698-41-1................................. o-Chlorobenzylidene malononitrile* 2699-79-8................................. Sulfuryl fluoride* 2937-50-0................................. Allylchloroformate 2941-64-2................................. Ethyl chlorothioformate 3048-64-4................................. Vinyl norbornene 3173-53-3................................. Cyclohexyl isocyanate* 3282-30-2................................. Trimethylacetyl chloride 3689-24-5................................. Tetraethyl dithiopyrophosphate (Sulfotep)* 3691-35-8................................. Chlorophacinone 4098-71-9................................. Isophorone diisocyanate 4109-96-0................................. Dichlorosilane 4300-97-4................................. Chloropivaloyl chloride 4418-66-0................................. Phenol, 2,2'-thiobis(4- chloro-6-methyl-) 5332-73-0................................. 3-Methoxypropyl amine 5798-79-8................................. Bromobenzyl cyanide 6427-21-0................................. Methoxymethyl isocyanate 6581-06-2................................. 3-Quinuclidinyl benzilate 6923-22-4................................. Monocrotophos* 7439-92-1................................. Lead & compounds including lead phosphate* 7439-96-5................................. Manganese & compounds 7439-97-6................................. Mercury & compounds including methyl mercury* 7440-02-0................................. Nickel and compounds* 7440-38-2................................. Arsenic & compounds* 7440-39-3................................. Barium & compounds 7440-41-7................................. Beryllium & compounds* 7440-43-9................................. Cadmium & compounds* 7440-48-4................................. Cobalt & compounds 7440-50-8................................. Copper & compounds 7440-62-2................................. Vanadium & compounds 7440-66-6................................. Zinc & compounds 7446-18-6................................. Thallium sulfate* 7446-70-0................................. Aluminum chloride 7521-80-4................................. Butyltrichlorosilane 7550-45-0................................. Titanium tetrachloride* 7580-67-8................................. Lithium hydride 7616-94-6................................. Perchloryl fluoride 7631-89-2................................. Sodium arsenate 7647-19-0................................. Phosphorus pentafluoride* 7664-38-2................................. Phosphoric acid* 7705-07-9................................. Titanium chloride 7719-09-7................................. Thionyl chloride* 7722-84-1................................. Hydrogen peroxide (concentration greater than 52%)* 7723-14-0................................. Phosphorus 7727-15-3................................. Aluminum bromide 7738-94-5................................. Chromic acid 7782-65-2................................. Germane 7782-68-5................................. Iodic acid 7783-07-5................................. Hydrogen selenide* 7783-41-7................................. Oxygen difluoride* 7783-54-2................................. Nitrogen trifluoride* 7783-61-1................................. Silicon tetrafluoride* 7783-70-2................................. Antimony pentafluoride 7783-71-3................................. Tantalum V fluoride 7783-79-1................................. Selenium hexafluoride* 7783-80-4................................. Tellurium hexafluoride* 7783-82-6................................. Tungsten hexafluoride 7784-46-5................................. Sodium arsenite* 7786-34-7................................. Mevinphos* 7787-71-5................................. Bromine trifluoride* 7789-21-1................................. Fluorosulfonic acid 7789-30-2................................. Bromine pentafluoride* 7789-59-5................................. Phosphorus oxybromide 7789-69-7................................. Phosphorus pentabromide 7789-75-5................................. Calcium fluoride 7790-94-5................................. Chlorosulfonic acid* 7791-23-3................................. Selenium oxychloride 7791-25-5................................. Sulfuryl chloride* 7803-49-8................................. Hydroxylamine* 7803-52-3................................. Stibine (antimony hydride)* 7803-62-5................................. Silane* 8001-35-2................................. Camphechlor 8006-61-9................................. Gasoline* 10025-67-9................................ Disulfur dichloride 10025-73-7................................ Chromic chloride 10026-13-8................................ Phosphorus pentachloride 10028-15-6................................ Ozone* 10034-85-2................................ Hydrogen iodide* 10035-10-6................................ Hydrogen bromide* 10265-92-6................................ Methamidophos* 10294-33-4................................ Boron tribromide* 10544-72-6................................ Nitrogen tetroxide 10544-73-7................................ Nitrogen trioxide 10545-99-0................................ Sulfur dichloride* 11099-02-8................................ Nickel oxide* 12002-03-8................................ Copper acetoarsenite* 12108-13-3................................ Manganese, tricarbonyl methylcyclopentadienyl 13071-79-9................................ Terbufos* 13194-48-4................................ Ethoprophos 13470-08-1................................ Titanium III fluoride 13637-63-3................................ Chlorine pentafluoride* 13863-41-7................................ Bromine chloride* 16752-77-5................................ Methomyl* 17462-58-7................................ iso-Butyl chloroformate 19624-22-7................................ Pentaborane* 20816-12-0................................ Osmium tetroxide* 20859-73-8................................ Aluminum phosphide* 22224-92-6................................ Fenamiphos 22967-92-6................................ Methyl mercury 23135-22-0................................ Oxamyl 23422-53-9................................ Formetanate hydrochloride 25321-14-6................................ Dinitrotoluene 25321-22-6................................ Dichlorobenzene 26419-73-8................................ Tirpate 27137-85-5................................ Trichloro (dichlorophenyl) silane 28772-56-7................................ Bromodiolone 30674-80-7................................ Methacryloyloxyethyl isocyanate 32315-10-9................................ Triphosgene